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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferons
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“It is suggested that increased serum iron and transferrin saturation blunt the action of interferon , as they have opposite effects on the immune system.”
Elevated serum iron predicts poor response to interferon treatment in patients with chronic HCV infection“Our study confirms the important role played by iron in the response to IFN treatment, suggesting that the use of rHuEPO induces a better response to IFN in patients with chronic hepatitis C by activation of erythropoiesis.”
“The sustained response rate was increased in some studies to 29% when iron reduction was undertaken along with interferon.”
“ Iron reduction has been reported to increase the therapeutic response to α interferon.”
“Uptake of iron and the cellular ferritin content also decreased by 50% when incubated with 10(4)U/ml of IFN-α.”
Mechanism of Decrease in Transferrin Receptor Synthesis by Interferon-α Treated Human Lymphoblastoid Cells.
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