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Cancer Chemotherapy and Pharmacology • 2004 | View Paper
“Analysis of RNA isolated from FAA-… to 100 micrograms/ml of FAA induced expression of tumor necrosis factor alpha (TNF-alpha) mRNA by 1 h and induced … within 3 h. The expression of all cytokine genes was diminished by 6 h. Interferon biological activity was detected … treatment with FAA.”
“The results from the present investigation demonstrate that in vivo administration of FAA induces in a dose-dependent manner high levels of serum interferon (IFN) within 4 hours in BALB/c, C57BL/6, and BALB/c nude mice.”