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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferons
supplement:
Diindolylmethane
Research Papers that Mention the Interaction
“ DIM and IFNγ produced an additive inhibition of cell proliferation and a synergistic increase in levels of major histocompatibility complex class-1 (MHC-1) expression, accompanied by increased levels of mRNAs of MHC-1-associated proteins and transporters.”
“ DIM synergistically augmented the IFNγ induced phosphorylation of signal transducer and activator of transcription factor 1, further evidence of DIM activation of the IFNγ pathway.”
“In cotreatments with IFNγ, DIM produced an additive activation of endogenous p69-OAS and of an OAS-Luc reporter and a synergistic activation of a GAS-Luc reporter.”
“We showed recently that DIM up-regulates the expression of interferon γ (IFNγ) in human MCF-7 breast cancer cells.”
Activation and Potentiation of Interferon-γ Signaling by 3,3′-Diindolylmethane in MCF-7 Breast Cancer Cells
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