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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Interferon Gamma-1B and Niacin

Research Papers that Mention the Interaction

Nicotinamide and 3-AB dose-dependently inhibited the induction of ICAM-1 expression by IFN-gamma or PHA on thyroid cells.
Immunology  •  1993  |  View Paper
Niacinamide primarily reduced IL-2 and IFN-gamma , while IL-10 predominantly reduced IL-1alpha and TNF-alpha.
Toxicology  •  1996  |  View Paper
Niacinamide reduced iNOS mRNA levels and markedly reduced IFN-gamma induction of endothelial class II MHC surface antigen.
Infection and immunity  •  1995  |  View Paper
Furthermore, the level of NO synthase mRNA was measured by Northern-blot analysis and we found that nicotinamide prevents expression of NO synthase mRNA in IFN-gamma- and LPS-stimulated cells.
The Biochemical journal  •  1994  |  View Paper