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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interferon Gamma-1B and Kaempferol

Research Papers that Mention the Interaction

Luteolin , the deglycosylated derivative of one of the major compositions, luteolin-7-glucoside, exerted inhibitory effects on TNF-alpha, IL-6 and IFN-gamma production in activated human whole blood with estimated IC(50)s of 42.73 microM, 44.86 microM and 3.34 microM, respectively.
Life sciences  •  2005  |  View Paper
Apigenin and luteolin also suppressed microglial TNF-α and IL-6 production stimulated by IFN-gamma challenge in the presence of CD40 ligation.
Journal of Neuroinflammation  •  2008  |  View Paper
Quercetin, apigenin, and luteolin also prevented IL-1beta- and IFN-gamma-mediated inhibition of insulin secretion.
Pancreas  •  2007  |  View Paper
Previously, we demonstrated that in vitro flavonoids, including luteolin and apigenin, inhibit proliferation and IFN-gamma production by murine and human autoimmune T cells.
Biochemical pharmacology  •  2005  |  View Paper
Kaempferol suppressed IFN-gamma and IL-2 production but not that of IL-4 by T cells and shifted the Th1/Th2 balance into the Th2 phenotype.
Clinical immunology  •  2002  |  View Paper