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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon Gamma-1B
supplement:
Kaempferol
Research Papers that Mention the Interaction
“ Luteolin , the deglycosylated derivative of one of the major compositions, luteolin-7-glucoside, exerted inhibitory effects on TNF-alpha, IL-6 and IFN-gamma production in activated human whole blood with estimated IC(50)s of 42.73 microM, 44.86 microM and 3.34 microM, respectively.”
Anti-inflammatory and antiviral effects of Glossogyne tenuifolia.“Apigenin and luteolin also suppressed microglial TNF-α and IL-6 production stimulated by IFN-gamma challenge in the presence of CD40 ligation.”
Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression“Quercetin, apigenin, and luteolin also prevented IL-1beta- and IFN-gamma-mediated inhibition of insulin secretion.”
“Previously, we demonstrated that in vitro flavonoids, including luteolin and apigenin, inhibit proliferation and IFN-gamma production by murine and human autoimmune T cells.”
“ Kaempferol suppressed IFN-gamma and IL-2 production but not that of IL-4 by T cells and shifted the Th1/Th2 balance into the Th2 phenotype.”
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