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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon Gamma-1B
supplement:
Genistein
Research Papers that Mention the Interaction
“ Genestein also inhibited expression when it was added to cultures between 8 and 24 h after IFN-gamma treatment.”
Expression and regulation of interferon-gamma-induced tryptophan catabolism in cultured skin fibroblasts.“ Genistein also modulates the expression of ICAM-1 on endothelial cells by potentiating the upregulating effect of TNF and IFN-gamma.”
“Being consistent with this, IFN-gamma induced increased tyrosine phosphorylation and this was inhibited by genistein.”
“Moreover, genistein significantly inhibited the expression of VEGF and IFN-gamma production (P < .01).”
Experimental study on genistein prevention and treatment of transplant arteriosclerosis in aortic transplants of rat.“ IFN-gamma production level in NC mice that received 20 mg/kg genistein was significantly lower than that in control NC mice.”
“The tyrosine kinase inhibitors, genistein (10(-7) - 10(-4) M) and herbimycin A (5.2 x 10(-9) - 1.74 x 10(-6) M), produced a powerful concentration-dependent inhibition of nitrite accumulation when added prior to stimulation with LPS and IFN-gamma.”
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