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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon Gamma-1B
supplement:
Epigallocatechin
Research Papers that Mention the Interaction
“Furthermore, both BC-P and purified EGC potentiated the ability of IFN-gamma to suppress IL-4-stimulated CCL26 secretion.”
Blackcurrant proanthocyanidins augment IFN-gamma-induced suppression of IL-4 stimulated CCL26 secretion in alveolar epithelial cells.“ EGCG , but not the related epigallocatechin, completely prevented the increase in epithelial (i.e., T84 cell monolayer) permeability caused by IFN-gamma exposure as gauged by transepithelial resistance and horseradish peroxidase flux; EGCG did not alleviate the barrier disruption induced by IL-4 or EPEC.”
“In the present study, we investigated whether EGCG could suppress the expression of IDO in murine bone marrow-derived dendritic cells (BMDCs) stimulated with IFN-gamma.”
“We found that EGCG inhibited the activation and binding of STAT1 to the IRF-1 promoter in response to IFN-gamma.”
(-)-Epigallocatechin gallate suppresses indoleamine 2,3-dioxygenase expression in murine dendritic cells: evidences for the COX-2 and STAT1 as potential targets.
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