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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Possible Interaction: Interferon Gamma-1B and 1-(P-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline
Research Papers that Mention the Interaction
“Taken together, these data strongly suggest that higenamine inhibits iNOS expression by inhibiting nuclear factor kappaB activation by LPS + IFN-gamma , which may be beneficial in inflammatory diseases in which enhanced formation of NO is the main causative factor.”
Inhibition of activation of nuclear factor kappaB is responsible for inhibition of inducible nitric oxide synthase expression by higenamine, an active component of aconite root.
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