Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Sulforaphane

Research Papers that Mention the Interaction

Administration of sulforaphane significantly enhanced the production of IL-2 and IFN-γ in metastatic tumor-bearing animals.
These data clearly suggest that sulforaphane effectively inhibited the spread of metastatic tumor cells through the stimulation of CMI, upregulation of IL-2 and IFN-γ , and downregulation of proinflammatory cytokines IL-1β, IL-6, TNF-α, and GM-CSF.
Immunopharmacology and immunotoxicology  •  2007  |  View Paper
The results obtained suggest that sulforaphane acts as a chemopreventive agent in human lymphoblastoid cells.
Acta biochimica Polonica  •  2004  |  View Paper
However, SFN strongly blocked the mRNA expressions of MIG, IP-10 and I-TAC induced by IFN-γ in INS‑1 cells.
International journal of molecular medicine  •  2017  |  View Paper
LPS-induced TRAM, TRIF, RIPK1, TRAF3, TNF-α, IL-1β and IFN-β were suppressed by 5 µM SFN.
Innate immunity  •  2016  |  View Paper
Additionally, posttreatment of sulforaphane inhibited levels of IL-6, IL-10, TNF-α, IFN-γ , and VEGF in peritoneal fluid and plasma.
Dose-response : a publication of International Hormesis Society  •  2019  |  View Paper