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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon-Alpha
supplement:
Sulforaphane
Research Papers that Mention the Interaction
“Administration of sulforaphane significantly enhanced the production of IL-2 and IFN-γ in metastatic tumor-bearing animals.”
“These data clearly suggest that sulforaphane effectively inhibited the spread of metastatic tumor cells through the stimulation of CMI, upregulation of IL-2 and IFN-γ , and downregulation of proinflammatory cytokines IL-1β, IL-6, TNF-α, and GM-CSF.”
Modulation of Cell-Mediated Immune Response in B16F-10 Melanoma-Induced Metastatic Tumor-Bearing C57BL/6 Mice by Sulforaphane“The results obtained suggest that sulforaphane acts as a chemopreventive agent in human lymphoblastoid cells.”
“However, SFN strongly blocked the mRNA expressions of MIG, IP-10 and I-TAC induced by IFN-γ in INS‑1 cells.”
Sulforaphane inhibits the interferon-γ-induced expression of MIG, IP-10 and I-TAC in INS‑1 pancreatic β-cells through the downregulation of IRF-1, STAT-1 and PKB.“LPS-induced TRAM, TRIF, RIPK1, TRAF3, TNF-α, IL-1β and IFN-β were suppressed by 5 µM SFN.”
“Additionally, posttreatment of sulforaphane inhibited levels of IL-6, IL-10, TNF-α, IFN-γ , and VEGF in peritoneal fluid and plasma.”
Sulforaphane Attenuates Endometriosis in Rat Models Through Inhibiting PI3K/Akt Signaling Pathway
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