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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Interferon-Alpha
supplement:
Oligomeric Procyanidin Complex
Research Papers that Mention the Interaction
“We found that IFN-γ profoundly impaired OPC proliferation and recruitment following adult spinal cord demyelination.”
Heparanome-Mediated Rescue of Oligodendrocyte Progenitor Quiescence following Inflammatory Demyelination“Here we report that OPC differentiation is inhibited by both effector T cells and IFNγ overexpression by astrocytes.”
“IL-9 plus IFN-γ promoted OPC proliferation and differentiation.”
IL-9 signaling affects central nervous system resident cells during inflammatory stimuli.“Further, treatment of CXCR3−/− OPC cultures with either IFN‐γ or CXCL10 resulted in reduced cell death supporting an important role for CXCL10 signaling in IFN‐γ‐mediated OPC apoptosis.”
“Primary bone marrow derived macrophages (BMDM) prepared from C57BL/6 mice treated with rIFN-γ exhibited greater inhibition of intracellular ΔfopC than wildtype U112 strain replication; whereas, IFN-γR KO macrophages showed no IFN-γ-dependent inhibition of ΔfopC replication.”
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