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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Interferon-Alpha
supplement:
NAD
Research Papers that Mention the Interaction
“Moreover, NAD+ treatment up-regulated the expressions of IL-13 and down-regulated the expression of IFN-γ and IL-17.”
NAD+ attenuates experimental autoimmune encephalomyelitis through induction of CD11b+ gr-1+ myeloid-derived suppressor cells“Additionally, IFN-γ resulted in a 23% depletion of intracellular NAD+ in HCAEC.”
“Conclusions: IFN-γ impairs endothelial glucose metabolism via altered tryptophan catabolism destabilizing HIF1, depletes NAD+ , and results in a metabolic shift toward increased fatty acid oxidation.”
Interferon-gamma Impairs Human Coronary Artery Endothelial Glucose Metabolism via Tryptophan Catabolism and Activates Fatty Acid Oxidation.“ IFN-γ activation of macrophages resulted in the highest induction of IDO but decreased intracellular NAD+ concentrations at both 24 and 48 hours.”
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