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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Interferon-Alpha and NAD

supplement:

NAD

Research Papers that Mention the Interaction

Moreover, NAD+ treatment up-regulated the expressions of IL-13 and down-regulated the expression of IFN-γ and IL-17.
Bioscience reports  •  2020  |  View Paper
Additionally, IFN-γ resulted in a 23% depletion of intracellular NAD+ in HCAEC.
Conclusions: IFN-γ impairs endothelial glucose metabolism via altered tryptophan catabolism destabilizing HIF1, depletes NAD+ , and results in a metabolic shift toward increased fatty acid oxidation.
Circulation  •  2021  |  View Paper
IFN-γ activation of macrophages resulted in the highest induction of IDO but decreased intracellular NAD+ concentrations at both 24 and 48 hours.
International journal of tryptophan research : IJTR  •  2018  |  View Paper