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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Methylselenocysteine

Research Papers that Mention the Interaction

The veto function of both MSC lines was enhanced in escalating IFN-γ environments.
Cell transplantation  •  2011  |  View Paper
IFN-γ inhibited proliferation and altered human and mouse MSC neural, adipocytic and osteocytic differentiation via the activation of IDO.
PloS one  •  2011  |  View Paper
Importantly, CsA exposure to IFNγ pre-stimulated MSC before administration, significantly enhanced the potency of MSCs in a human relevant humanised mouse model of acute Graft versus Host Disease.
Stem cell research & therapy  •  2021  |  View Paper
Both MSC can inhibit lymphocyte proliferation and suppress IFN-γ secretion induced by PHA in vitro.
Zhongguo shi yan xue ye xue za zhi  •  2016  |  View Paper
Upon IFNγ prelicensing, both MSC populations inhibit T-cell effector functions.
Molecular therapy : the journal of the American Society of Gene Therapy  •  2015  |  View Paper
For both T and B cells, MSC co-colture induced a statistically significant increase in IL-10 and TGFβ and decrease of GM-CSF and IFNγ , as compared with MV incubation.
Stem cells and development  •  2014  |  View Paper
In vitro, IFNγ significantly increased MSC proliferation, a response mediated by Shh that was blocked by 5E1 antibody.
The MSC population collected from bone marrow of PBS- or IFNγ-treated mice showed that IFNγ significantly increased the percentage of all MSC cell lines in S phase, with the exception of the stMSCsShhKO cells.
We tested the hypothesis that IFNγ drives MSC proliferation and recruitment, a response mediated by Shh signaling.
PloS one  •  2013  |  View Paper
In a related article, Liu et al. investigated how interferon-gamma IFN-γ ) treatment can influence the metabolic state of MSC to promote immunomodulatory properties [5].
Stem cells  •  2019  |  View Paper