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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon-Alpha
supplement:
Manganese
Research Papers that Mention the Interaction
“ IFN-γ was inhibited by 8×10(-4) mmol/L Mn for 48 h. This study demonstrates that excess Mn affects cytokine mRNA expression and causes immunosuppression in chicken spleen lymphocytes.”
The effect of manganese-induced toxicity on the cytokine mRNA expression of chicken spleen lymphocytes in vitro.“ Mn also potentiated IFNγ‐ and TNFα‐induced phosphorylation of extracellular response kinase (ERK), p38, and JNK, as well as cytokine‐induced activation of a fluorescent NF‐κB reporter construct in transgenic astrocytes.”
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