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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Leucine

supplement:

Leucine

Research Papers that Mention the Interaction

Application of IFN-γ to lung cancer cells led to enhanced expression of RNase L that compensated the RLI inhibition and restored the cytoplasmic and nuclear function of RNase L, leading to apoptosis of lung cancer cells.
Cell Death & Disease  •  2019  |  View Paper
We found that IFN-tau increased the synthesis of the cellular antiviral factors, such as 2',5'-oligoadenylate synthetase/RNase L and MxA protein.
Pathologie-biologie  •  2008  |  View Paper
Two … IFN-τ treatment in macrophages may account for this inhibition: (i) the … cellular antiviral factors such as 2′,5′-oligoadenylate synthetase/RNase L and MxA protein and (ii) an increased production of MIP-1α, MIP-1β, … are natural ligands of CCR5, the principal coreceptor of HIV on macrophages.
Journal of Virology  •  2003  |  View Paper
In MEFs, RNase L gene knockout decreased induction of IFN-β by encephalomyocarditis virus infection or poly(rI):poly(rC) (pIC) transfection.
mBio  •  2014  |  View Paper
Both DA L and GDVII L block IFN-β gene transcription in infected mice; however, IFN-β mRNA is expressed at low levels in the central nervous systems of mice persistently infected with DA.
Cardiovirus L is a multifunctional protein that blocks beta interferon ( IFN-β ) gene transcription.
Journal of Virology  •  2010  |  View Paper