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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Interferon-Alpha
supplement:
Iodine
Research Papers that Mention the Interaction
“Our results indicate that Y and/or I at position 86 and Y at position 90 are very important in antiproliferative activity of human IFN-α.”
Human IFN-α Protein Engineering: The Amino Acid Residues at Positions 86 and 90 Are Important for Antiproliferative Activity1“En II regulates production of pregenomic RNA, a key product of HBV replication, more strongly than En I. Although IFN-α has been found to suppress En I activity, its effect on En II activity has not been examined.”
“A second GAS element PE I ), between ISRE and PE II, was ineffective in supporting a response to IFN-γ.”
“Strikingly, IFN-γ interacted synergistically with iodine to enhance ICAM-1 expression on thyrocytes.”
“These findings suggest that iodine and IFN-γ cooperate to promote thyroidal expression of ICAM-1 in this mouse model of thyroiditis, highlighting the complex interplay present in the pathogenesis of Hashimoto’s thyroiditis.”
Iodine and IFN-γ Synergistically Enhance Intercellular Adhesion Molecule 1 Expression on NOD.H2h4 Mouse Thyrocytes1
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