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“All isolates contained identical mutations in trpA and developed aberrant bodies within intracellular inclusions, visualized by transmission electron microscopy, even when supplemented with indole following IFN-γ treatment.”
“In vitro studies have confirmed the capacity of indole to mitigate the effects of IFNγ ; it has been suggested that a perturbed vaginal microbiome may provide a source of indole in vivo.”