Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Ginseng



Research Papers that Mention the Interaction

Interestingly, in acute EAE rats, pretreatment with KRGE significantly reduced the population of CD4+, CD4+/IFN-γ+, and CD4+/IL-17+ T cells in the spinal cord and lymph nodes, corresponding to the downregulation of mRNA expression of IFN-γ , IL-17, and IL-23 in the spinal cord.
Molecular Neurobiology  •  2015  |  View Paper
These findings suggest that Red Ginseng inhibits allergic reactions to food by preventing reductions in the ratio of IFN-γ to IL-4 and in IL-12 production induced by dietary antigens in spleen cells, and/or increasing the expression of CD8 and IFN-γ in the small intestine.
Journal of ethnopharmacology  •  2010  |  View Paper
In immunohistopathologic analysis, KRG , ATP, BYO, KRG + ATP, and KRG + BYO groups showed significantly reduced expression levels of IFN-γ at 1 h, 6 h, and 48 h (all p < 0.05).
Journal of ethnopharmacology  •  2021  |  View Paper
In addition, ginseng reduces the expression levels of proinflammatory cytokines ( IFN-γ , TNF-α, IL-2, IL-4, IL-5, IL-6, IL-8) and chemokines produced by airway epithelial cells and macrophages, thus preventing weight loss.
Journal of ginseng research  •  2020  |  View Paper
The data show that intraperitoneal administration of KRG compromises MDSC function and induces T cell proliferation and the secretion of IL-2 and IFN-γ , while it does not exhibit direct cytotoxicity on tumor cells and reduced MDSC accumulation.
Journal of ginseng research  •  2011  |  View Paper