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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon-Alpha
supplement:
Genistein
Research Papers that Mention the Interaction
“Furthermore, the treatment with genistein also caused a significant increment in interferon gamma ( IFN-γ).”
Genistein induces a protective immunomodulatory effect in a mouse model of cervical cancer.“When mouse splenocytes were stimulated with lipopolysaccharide, E2, Gen , and Dai suppressed the production of IFN-γ.”
Estrogenic compounds suppressed interferon-gamma production in mouse splenocytes through direct cell-cell interaction“Daidzein, genistein , luteolin and apigenin, the main flavonoids present in diffusates of elicited cotyledons, suppressed the NO production by LPS + IFNγ activated macrophages in a concentration-dependent manner, with IC50 values of 81.4 μM, 34.5 μM, 38.6 μM and 10.4 μM respectively.”
“ Genistein suppressed the production of IFN-γ and enhanced IL-10 secretion in splenocyte and brain.”
Effect of oral genistein administration in early and late phases of allergic encephalomyelitis
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