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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Interferon-Alpha
supplement:
Garlic
Research Papers that Mention the Interaction
“The chronic eating of garlic was found to maintain IFN-alpha at high levels for at least 7 days.”
Systemic production of IFN-alpha by garlic (Allium sativum) in humans.“Serum IFN-γ concentration significantly increased in the MEAS 20 and 80 groups in comparison to the control, albendazole and MEAS 10 groups (P < 0.05).”
“The CD4+/CD8+ ratio and in vitro IFN-γ production of splenocytes were significantly increased in AGE group.”
Effect of aged garlic extract on immune responses to experimental fibrosarcoma tumor in BALB/c mice.“… garlic treatment group showed … decreased production of IFN‐γ from 101.73 ± 4.62 to 74.64 ± 4.64 pg/mL and significantly increased IL‐4 production from 26.… ± 3.35 to 83.92 ± 6.56 pg/mL (p < 0.001) in the supernatant of PHA induced spleen lymphocytes.”
“Results: The findings reveal that AGE increased the level of IFN-λ and IL-4 cytokines produced by splenocytes stimulated by specific tumor antigen and decreased the number of Treg cells in the spleen (p<0.05).”
Evaluation of The Number of CD4+ CD25+ FoxP3+ Treg Cells in Normal Mice Exposed to AFB1 and Treated with Aged Garlic Extract“The CD4+/CD8+ ratio and in vitro IFN-γ production of splenocytes were significantly increased in AGE group.”
“In addition, the hypothesis that garlic can improve cellular immunity with raising the expression of IFNγ and of iNOS genes confirmed.”
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