Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Interferon-Alpha and Fish Oils

Research Papers that Mention the Interaction

Fish oil supplementation during lactation resulted in increased in vitro IFN-γ production in the children 2 yr after the supplementation was given, which may reflect a faster maturation of the immune system.
Lipids  •  2005  |  View Paper
…,FO reduced mRNA expression … markers (T-bet, IFN-γ ) and increased Th2 markers (GATA3, IL-4), concomitant with reduced inflammatory cytokines (IL-1β, IL-6, IL-12p70, TNF-α), …-1α, MIP-2), and levels of activated central regulators of inflammatory signaling (NF-κB, STAT-1, STAT-3) (P<.05).
The Journal of nutritional biochemistry  •  2020  |  View Paper
In contact-dependent co-cultures, FO reduced inflammatory (IL-6, TNFα, IFN-γ ) and macrophage chemotactic (CCL2, CCL7, CCL3) mRNA expression and/or secreted protein, NF-κB p65 activation, ROS accumulation, NLRP3 inflammasome priming (Nlrp3, Il1β mRNA) and activation (caspase-1 activity) compared to CON (P<.05).
The Journal of nutritional biochemistry  •  2019  |  View Paper
Simultaneously, FO diet induced more necrotic liver tissues and apoptotic hepatocytes, and up-regulated the hepatic expression of TNF-α and IFN-γ after Con A challenge.
The Journal of toxicological sciences  •  2014  |  View Paper
IFN-y production was reduced by SO or FO feeding compared with feeding the COor OO-rich diets (Table 1).
Lipids  •  2007  |  View Paper