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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Interferon-Alpha
supplement:
Fish Oils
Research Papers that Mention the Interaction
“ Fish oil supplementation during lactation resulted in increased in vitro IFN-γ production in the children 2 yr after the supplementation was given, which may reflect a faster maturation of the immune system.”
Fish oil supplementation of lactating mothers affects cytokine production in 2 1/2-year-old children“…,FO reduced mRNA expression … markers (T-bet, IFN-γ ) and increased Th2 markers (GATA3, IL-4), concomitant with reduced inflammatory cytokines (IL-1β, IL-6, IL-12p70, TNF-α), …-1α, MIP-2), and levels of activated central regulators of inflammatory signaling (NF-κB, STAT-1, STAT-3) (P<.05).”
Dietary long-chain n-3 PUFA mitigate CD4+ T cell/adipocyte inflammatory interactions in co-culture models of obese adipose tissue.“In contact-dependent co-cultures, FO reduced inflammatory (IL-6, TNFα, IFN-γ ) and macrophage chemotactic (CCL2, CCL7, CCL3) mRNA expression and/or secreted protein, NF-κB p65 activation, ROS accumulation, NLRP3 inflammasome priming (Nlrp3, Il1β mRNA) and activation (caspase-1 activity) compared to CON (P<.05).”
“Simultaneously, FO diet induced more necrotic liver tissues and apoptotic hepatocytes, and up-regulated the hepatic expression of TNF-α and IFN-γ after Con A challenge.”
“ IFN-y production was reduced by SO or FO feeding compared with feeding the COor OO-rich diets (Table 1).”
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