supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Interferon-Alpha
supplement:
Copper
Research Papers that Mention the Interaction
“In vitro, increased Cu levels inhibited IFN-γ production.”
Zinc/copper imbalance reflects immune dysfunction in human leishmaniasis: an ex vivo and in vitro study“ IFN-alpha was observed to dose-… immunoreactive protein levels of copper , zinc-and manganese-dependent SOD as well as the enzyme activities of GPx, and decrease the lipid peroxidation product … oxidative burst both in stressed hepatocytes and activated HSCs; GPx activities, however, were not detected in the latter cells.”
“ IFN-γ activation of macrophages also limits availability of copper in the phagosome, forcing Histoplasma reliance on the high affinity Ctr3 copper importer for copper acquisition.”
Histoplasma Responses to Nutritional Immunity Imposed by Macrophage Activation
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback