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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferon-Alpha
supplement:
Caffeine
Research Papers that Mention the Interaction
“Regarding cytokine analysis, a negative correlation between daily caffeine consumption and serum level of IFNγ … found (p = 0.03, r = –0.2); furthermore, patients with a high intake of caffeine showed lower … levels of IFNα (p = 0.02), IL-17 (p = 0.01) and IL-6 (p = 0.003).”
Caffeine intake influences disease activity and clinical phenotype in systemic lupus erythematosus patients“ Caffeine was found to potentiate the X-ray-induced aberration yield in both normal fibroblast and lymphoblastoid cells.”
“Here we report that caffeine potentiates the induction of chromosomal breaks in G2 arrested AT heterozygote and normal lymphoblastoid cells , but not in homozygous AT lymphoblastoid cells.”
“ Alpha-interferon has shown synergism with other anti-HSV drugs such as caffeine , trifluorothymidine (TFT), DMSO, and nonoxynol-9.”
“We found that caffeine and anti-PD1 mAb combination therapy significantly increased intra-tumoral TNF-α and IFN-γ levels.”
Caffeine-enhanced anti-tumor activity of anti-PD1 monoclonal antibody.“Intranasal administration of the adenosine receptor antagonist caffeine substantially enhanced the frequency and number of parenchymal CD4+ T cells as well as both CD69 expression and IFNγ production.”
“ Interferon-alpha has shown synergism with other anti-HSV drugs such as caffeine , trifluorothymidine, dimethyl sulfoxide and nonoxynol-9, and ascorbic acid shows promising effects against HSV.”
Topical antiviral agents for herpes simplex virus infections.
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