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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Ascorbate

Research Papers that Mention the Interaction

Cytokine secretion was downregulated by ascorbate even to lower values than those observed in basal cultures ( IFNγ : p=0.0312; TNFα: p=0.0312; IFNα: p=0.0312; and IL-6: p=0.0078).
RESULTS The addition of as orbate to in vitro culture gliadin-challenged biopsies blocked the secretion of nitrites (p=0.013), IFN γ (p =0.0207), TNFα (p=0.0099), IFNα (p=0.0375), and IL-6 (p=0.0036) compared to samples from non-ascorbate supplemented culture.
Allergologia et immunopathologia  •  2012  |  View Paper
IFNα (50–1,000 IU/ml) inhibited the stimulation of alkaline phosphatase specific activity induced by ascorbate and dexamethasone.
Journal of cellular biochemistry  •  1999  |  View Paper