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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Interferon-Alpha
supplement:
Ascorbate
Research Papers that Mention the Interaction
“Cytokine secretion was downregulated by ascorbate even to lower values than those observed in basal cultures ( IFNγ : p=0.0312; TNFα: p=0.0312; IFNα: p=0.0312; and IL-6: p=0.0078).”
“RESULTS The addition of as orbate to in vitro culture gliadin-challenged biopsies blocked the secretion of nitrites (p=0.013), IFN γ (p =0.0207), TNFα (p=0.0099), IFNα (p=0.0375), and IL-6 (p=0.0036) compared to samples from non-ascorbate supplemented culture.”
Ascorbate-dependent decrease of the mucosal immune inflammatory response to gliadin in coeliac disease patients.“ IFNα (50–1,000 IU/ml) inhibited the stimulation of alkaline phosphatase specific activity induced by ascorbate and dexamethasone.”
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