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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interferon-Alpha and Antioxidants

Research Papers that Mention the Interaction

Importantly treatment with an antioxidant led to increased IFN-γ and reduced IL-10 production in human chronic Hep-B/C samples suggesting overall a proximal regulatory role for iCa2+ influx, ROS, and IL-10 in determining the effector/ suppressive axis of CD8+ T cells.
Frontiers in Immunology  •  2020  |  View Paper
The combination of rectal and topical dosage forms of IFN-α2b with antioxidants was more effective than monotherapy with the rectal suppositories in preventing repeated hospitalization for ARI.
Terapevticheskii arkhiv  •  2018  |  View Paper
These results indicate that NO and antioxidants may attenuate vascular inflammation by antagonizing the effects of intracellular reactive oxygen species generation by IFN-γ , which is necessary for MHC-II gene transcription.
The Journal of Biological Chemistry  •  2002  |  View Paper
Furthermore, treatment of NKT cells with antioxidants led to reduced frequencies of IFN-γ– and IL-17–expressing cells, indicating that ROS play a role in regulating the inflammatory function of NKT cells.
The Journal of Immunology  •  2017  |  View Paper