Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Interferon-Alpha and Andrographolide

Research Papers that Mention the Interaction

AD … IFN-γ were lower than those in the non-interference groups and the mRNA expression levels decreased, RIG-I, IPS-1, IRF-7, IRF-3 …).ConclusionsThe RLRs mediated viral recognition provided a potential molecular target for acute viral infections and andrographolide could ameliorate H1N1 virus-induced cell mortality.
Chinese Journal of Integrative Medicine  •  2014  |  View Paper
The elevation of inflammatory cytokines including IL-6, IL-17A, TNF-α as well as IFN-γ in colonic tissues levels were decreased after administration of andrographolide sulfonate.
International immunopharmacology  •  2020  |  View Paper
In addition, andrographolide treatment significantly (P<0.05) decreased the level of serum pro-inflammatory cytokine, IFN-γ (1.4-fold) whilst the anti-inflammatory cytokines, IL-10 and IL-4 were increased 2.3- and 2.6-fold respectively.
Tropical biomedicine  •  2019  |  View Paper
AG suppressed the production of nitric oxide (NO) and prostaglandin E2 (PGE2), as well as the mRNA … inducible NO synthase (iNOS), tumor necrosis factor-alpha (TNF-α), cyclooxygenase (COX)-2, and interferon-beta ( IFN-β ) in a dose-dependent manner in both …-) activated RAW264.7 cells and peritoneal macrophages.
Evidence-based complementary and alternative medicine : eCAM  •  2013  |  View Paper