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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Insulin and Zinc Cation

drug:

Insulin

supplement:

Zinc Cation

Research Papers that Mention the Interaction

Zinc chelation by DEDTC lowered INS-1E insulin content and insulin expression.
PloS one  •  2009  |  View Paper
Infusion of supraphysiological perfusate Zn2+ (>15 μM) mimicked the inhibitory effect of insulin and chloroquine on lysosomal proteolysis.
Diabetes  •  1991  |  View Paper
These results are discussed in light of the modes of interactions of Zn(II) and Cu(II) ions with insulin.
Inorganic chemistry  •  2018  |  View Paper
The results obtained indicate that Zn(II) ions might suppress fibrillation of insulin at its release sites and in circulation.
The Biochemical journal  •  2010  |  View Paper