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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Insulin
supplement:
Zinc Cation
Research Papers that Mention the Interaction
“ Zinc chelation by DEDTC lowered INS-1E insulin content and insulin expression.”
“Infusion of supraphysiological perfusate Zn2+ (>15 μM) mimicked the inhibitory effect of insulin and chloroquine on lysosomal proteolysis.”
Effect of Zn2+ on the Proteolytic Inhibitory Action of Insulin and Biguanide Antihyperglycemic Drugs“These results are discussed in light of the modes of interactions of Zn(II) and Cu(II) ions with insulin.”
Gly-His-Thr-Asp-Amide, an Insulin-Activating Peptide from the Human Pancreas Is a Strong Cu(II) but a Weak Zn(II) Chelator.“The results obtained indicate that Zn(II) ions might suppress fibrillation of insulin at its release sites and in circulation.”
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