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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“ Yohimbine did not significantly influence most parameters but significantly potentiated the rise in insulin , blunted the increase in glucose, and prevented the fall in noradrenaline.”
Adrenoceptors mediating the cardiovascular and metabolic effects of alpha-methylnoradrenaline in humans.“It is well known that yohimbine , an alpha 2-adrenoceptor-blocking agent, reduces the secretion of insulin and the platelet factors.”
“Moreover, the treatment effects were dose-dependent, with improvements in plasma levels of insulin of 20% and 29% following treatment with 10 mg and 20 mg of yohimbine , respectively.”
“Furthermore, glucose oxidation rates were decreased with epinephrine, independent of the exocytosis of insulin , which was blocked with yohimbine.”
Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells“ Yohimbine caused prolonged increases in plasma norepinephrine and insulin levels compared to atipamezole, possibly because of its longer half-life elimination.”
“This Leu-Enk-evoked insulin release was significantly (p < 0.05) blocked by atropine, naloxone and yohimbine (all at 10−6M).”
“in rats that were given saline into the third cerebral ventricle, phentolamine and antazoline, but not yohimbine and idazoxan, increased plasma levels of insulin.”
“During the clonidine infusion midaglizole did not elicit any significant rise in plasma insulin, whereas yohimbine increased plasma insulin significantly.”
“The highest yohimbine infusion (50 nmol/kg/min) blocked the clonidine-induced responses of glucagon, insulin and glucose.”
“3 Yohimbine transiently increased plasma insulin and the effect was dose‐dependent.”
“ Yohimbine also induced a transient increase in plasma insulin level and increased heart rate and blood pressure.”
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