Possible Interaction: Insulin and Xylose

“Significantly lower serum levels of insulin were observed at 15 min and 30 min after consuming the xylose-containing drinks compared to the control group.”

“Although insulin accelerated the disappearance rate of d-xylose in nondiabetics, it had no effect on blood levels of d-xylose in insulin-treated diabetic patients.”

“The stimulatory effect of insulin on xylose uptake could be correlated with binding to the high-affinity site.”

“ Insulin , if added in vitro, enhances xylose uptake and both free dGlc and 2-deoxyglucose 6-phosphate (dGlc-60P) in the intracellular water.”

“ Insulin stimulated the membrane transport of d-xylose into the intact rat diaphragm preparation, while THAM had no effect.”

“In cut muscle fiber preparations, in which insulin significantly increases the rate at which D-xylose equilibrates between cell water and external medium, DNP does not increase the rate of D-xylose entry, but does abolish the effect of insulin in this preparation.”

“ Insulin increases the apparent intracellular distribution of D-xylose in both muscles in all three types of rats.”

“In conclusion, xylose showed an acute suppressive effect on the postprandial glucose and insulin surges.”

“One-hour cellular uptake of D-xylose was enhanced by insulin , chymotrypsin, and trypsin.”

“Summary Insulin markedly increased the volume of distribution of L-arabinose and D-xylose and accelerated the disappearance of D-galactose and 2-deoxy-D-glucose from the blood in functionally nephrectomized rats.”