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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Conclusion/interpretationSupplementation with high-dose thiamine may prevent deterioration in fasting glucose and insulin , and improve glucose tolerance in patients with hyperglycemia.”
High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind cross-over trial“With oral thiamine therapy , her insulin requirement decreased by 30% over a 20 month period.”
“The data suggest that thiamine inhibits human infragenicular ASMC proliferation induced by high glucose and insulin.”
“PREVIOUS work has demonstrated that in pancreatic diabetes a disturbance of the thiamine phosphorylation processes occurs and that the administration of insulin enhances the phosphorylation of thiamine provided that a sufficient amount of this substance is available to the organism1.”
“ Thiamin deficiency resulted in increased plasma glucose (18%) and lactate (3- to 4-fold) as well as in a 30% decrease in insulin and an increase in glucagon (2.6-fold) and corticosterone (3.6-fold).”
Thiamin deficiency impairs endotoxin-induced increases in hepatic glucose output.“Decrease in insulin requirement with institution of high-dose of thiamine has been reported [4].”
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