Possible Interaction: Insulin and Taurine

“Lampson, Kramer and Schaffer5 found that taurine potentiated the effect of insulin and influenced activity of phosphorylase a and glycogen synthase I.”

“In the cortex of APP/PS1 mice, taurine slightly decreased insoluble fraction of Aβ.”

“Nutritional intervention with taurine , phenyl alanine or branched chain amino acids can improve insulin sensitivity and post-prandial glucose disposal.”

“The effects of magnesium taurate in diabetes deserve particular attention, since both magnesium and taurine may improve insulin sensitivity, and also may lessen risk for the micro- and macrovascular complications of diabetes.”

“Lampson et al. (9) reported that taurine was capable of enhancing the effects of insulin on cardiac glycolysis, glycogenesis and oxygen consumption.”

“Both metformin and insulin improved taurine and hypotaurine metabolism, and α-GI promoted several amino acid pathways.”

“The results indicated that taurine can improve insulin sensitivity through remediating lipid metabolism disorder and regulating the expressions of IRS and GLUT4.”

“Surprisingly, we found that neurons express the gene for insulin and that taurine had a significant role in regulating insulin gene expression.”

“The results showed that, the release of insulin from islet cells treated by STZ could be inhibited by taurine , gene expression of insulin, PDX-1 and NeuroD1 in STZ group decreased significantly, which were up-regulated by taurine administration.”

“ Tau supplementation improved insulin sensitivity in females and β-cell function in males.”