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Last Updated: 3 years ago

Possible Interaction: Insulin and Soy Isoflavones

drug:

Insulin

supplement:

Soy Isoflavones

Research Papers that Mention the Interaction

In addition, the effect of soy isoflavones on insulin was also significant: -0.43 μIU/mL (95% CI: -0.71 to -0.14 μIU/mL), as was the effect on homeostasis model assessment insulin resistance (HOMA-IR): -0.52 (95% CI: -0.76 to -0.28).
Molecular nutrition & food research  •  2016  |  View Paper
RESULTS After … group, so isoflavone ad ulin (- 1.2 ± 4.0 vs +2.8 ± 4.7 μIU/mL; P < .001) and homeostasis model of assessment-estimated insulin resistance (-0.3 ± …; P < .001) and increased the quantitative insulin sensitivity check index (+0.0009 ± 0.01 vs -0.01 ± 0.03; P = .01).
The Journal of clinical endocrinology and metabolism  •  2016  |  View Paper
A unique finding was that SPI supplementation to the high-fat diet reduced plasma insulin by 11% (p < 0.05), MCP-1 by 21% (p = 0.03), and tumor necrosis factor-α (TNF-α) by 50% (p = 0.05) compared to casein.
Journal of agricultural and food chemistry  •  2013  |  View Paper