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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Insulin and Sodium Cholate

drug:

Insulin

supplement:

Sodium Cholate

Research Papers that Mention the Interaction

Although Pluronic F68 (0.5%) did not significantly alter the in vitro insulin degradation half-life T50%, sodium cholate (0.5%) increased the degradation T50% of insulin by 56% (from 13.6 ± 1.6 to 22.1 ± 2 min).
Drug development and industrial pharmacy  •  2001  |  View Paper
Enzyme inhibitors like bacitracin and sodium cholate noticeably enhanced the relative pharmacological bioavailability of insulin when given intratracheally with insulin to normal rats.
International journal of pharmaceutics  •  1999  |  View Paper
Different types of enzyme inhibitors, like sodium cholate , camostat, mesilate, bacitracin, leupeptin, and so forth, have been used to prevent insulin from enzymatic degradation.
Journal of pharmaceutics  •  2014  |  View Paper