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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Insulin
supplement:
Sodium Cholate
Research Papers that Mention the Interaction
“Although Pluronic F68 (0.5%) did not significantly alter the in vitro insulin degradation half-life T50%, sodium cholate (0.5%) increased the degradation T50% of insulin by 56% (from 13.6 ± 1.6 to 22.1 ± 2 min).”
Enhancement of Absorption of Insulin-Loaded Polyisobutylcyanoacrylate Nanospheres by Sodium Cholate After Oral and Subcutaneous Administration in Diabetic Rats“Enzyme inhibitors like bacitracin and sodium cholate noticeably enhanced the relative pharmacological bioavailability of insulin when given intratracheally with insulin to normal rats.”
“Different types of enzyme inhibitors, like sodium cholate , camostat, mesilate, bacitracin, leupeptin, and so forth, have been used to prevent insulin from enzymatic degradation.”
Emerging Trends in Noninvasive Insulin Delivery
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