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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“There was a statistically significant increase in plasma insulin concentrations during the quinine infusion and fall in plasma glucose concentration (P < 0.001).”
Effect of quinine therapy on plasma glucose and plasma insulin levels in pregnant women infected with Plasmodium falciparum malaria in Gezira state.“Also, quinine has been reported to stimulate insulin release from cultured islet cells [9].”
“This study shows that chronic administration of quinine increases plasma insulin levels, accelerates disposal of oral or intravenous glucose but does not cause hypoglycaemia in normal rats.”
Glucose homeostasis in rats treated acutely and chronically with quinine.“Plasma insulin concentrations were significantly higher in the knife-cut animals and were reduced toward control levels by quinine treatment.”
“ Quinine increases insulin release in vitro.”
“In the absence of glucose, 100 microM quinine stimulated 45Ca net uptake, 45Ca outflow rate and insulin release.”
“At higher concentrations (0.25-0.5 mM), quinine inhibited both 45Ca net uptake and insulin release.”
“It is proposed that the inhibitory effect of quinine , at high concentrations, upon insulin release may be due to a direct interference with the transport of Ca across the membrane system(s) in the islet cells.”
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