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Last Updated: a year ago

Possible Interaction: Insulin and Phenylalanine





Research Papers that Mention the Interaction

At day 28, insulin increased tCys (+8%), and the insulin-induced suppression of taurine and phenylalanine observed at day 0, but not that of BCAAs, was significantly impaired.
The Journal of nutrition  •  2018  |  View Paper
Nutritional intervention with taurine, phenyl alanine or branched chain amino acids can improve insulin sensitivity and post-prandial glucose disposal.
Current protein & peptide science  •  2009  |  View Paper
Bovine insulin enhanced the phenylalanine extraction when added to the medium at 250 ng/ml whereas no significant change was observed below this concentration.
Comparative biochemistry and physiology. Comparative physiology  •  1993  |  View Paper
In the intact rat hemidiaphragm in vitro 1 mU of insulin per ml caused a marked increase (40–70 per cent) of the incorporation of 14C-labelled phenylalanine into protein.
Acta physiologica Scandinavica  •  1966  |  View Paper
Insulin … phenylalanine rate of appearance (μmol·kg-1·min-1), indicating suppression of muscle proteolysis, in both the control (1.02 ± 0.04 vs 0.76 ± … (0.89 ± 0.07 vs 0.61 ± 0.03) experiments, but the change was not different between the two experiments (P > 0.05).
American journal of physiology. Endocrinology and metabolism  •  2016  |  View Paper
Importantly, insulin increased net Leu and Phe balance across the leg and the balance between muscle protein synthesis and breakdown, but these changes were 45-140% lower (P < 0.03) in Pred than in placebo.
Insulin in both trials similarly suppressed whole body flux of Leu and Phe.
American journal of physiology. Endocrinology and metabolism  •  2009  |  View Paper
CONCLUSION In summary, ph nylalanine in an amount moderately greater than that in a large protein meal stimulates an increase in ins ulin an d glucagon concentration.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme  •  2006  |  View Paper
In the hormone-infused arms, the addition of either insulin or IGF-I promoted greater positive shifts in phenylalanine balance than the aa alone arm (P < 0.01).
The Journal of clinical investigation  •  1995  |  View Paper
Insulin also reduced (< 0.01) whole-body protein synthesis estimated from both the leucine model (nonoxidative leucine disposal) and the phenylalanine model (disposal of phenylalanine not accounted by its conversion to tyrosine).
The Journal of clinical investigation  •  1995  |  View Paper
The release of tyrosine and phenylalanine was significantly decreased from both leg and arm tissues (protein degradation) in response to insulin.
The American journal of physiology  •  1994  |  View Paper
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