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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Insulin and Perillyl Alcohol

drug:

Insulin

supplement:

Perillyl Alcohol

Research Papers that Mention the Interaction

In fibroblasts, insulin increased the enzymatic activity of GGTase II 2.5-fold after 1 h of incubation, an effect that is blocked by perillyl alcohol , an inhibitor of prenyltransferases, but not by the geranylgeranyltransferase I inhibitor, GGTI-298, or the farnesyltransferase inhibitor, α-hydroxyfarnesylphosphonic acid.
The Journal of Biological Chemistry  •  1999  |  View Paper