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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Insulin
supplement:
Masoprocol
Research Papers that Mention the Interaction
“In the HFrD treatment group, NDGA administration by oral gavage decreased plasma levels of TG, glucose, FFA, and insulin , increased hepatic mitochondrial fatty acid oxidation and attenuated hepatic TG accumulation.”
Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis“The results indicate that masoprocol significantly increased glucose uptake by adipocytes in both the absence and presence of insulin.”
“These results provide an explanation at the cellular level for the observation that masoprocol decreases serum glucose, insulin , and FFA concentrations in rodent models of type 2 diabetes.”
“ Masoprocol treatment resulted in significantly (P < .05 to .001) lower values for … (120 +/- 3 v 164 +/- 5 mm Hg), as well as plasma insulin (30 +/- 5 v 44 +/- 4 microU/mL), free fatty acid (551 +/- 20 v … microEq/L), and triglyceride (79 +/- 5 v 219 +/- 32 mg/dL) concentrations.”
“Dietary administration of NDGA decreased plasma levels of TG, glucose, and insulin , and attenuated hepatic TG accumulation.”
Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats
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