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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“In particular it has been shown that magnesium plays the role of a second messenger for insulin action; on the other hand, insulin itself has been demonstrated to be an important regulatory factor of intracellular magnesium accumulation.”
Magnesium and glucose homeostasis“There is potential interaction with insulin, in that magnesium causes hyperglycemia, which requires insulin to counteract it.”
“In fact, in vitro and in vivo studies have demonstrated that insulin may modulate the shift of magnesium from extracellular to intracellular space.”
“Angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and insulin treatment may also affect the level of potassium and Mg.”
“In contrast, at close to neutral pH, when all the carboxylate groups are deprotonated and negatively charged, the charge-neutralizing effect of magnesium , calcium, and zinc, in particular, on the electrophoretic mobility of insulin is significant.”
“Co-relation of magnesium with FBS (r = -0.55, p<0.0001), insulin (r = -0.45, p< 0.0001) and HOMA-IR (r = -0.52, p<0.0001) was significant.”
“A mechanism for the INSTI-induced hyperglycaemia was hypothesized to be due to chelation of magnesium , thereby inhibiting the release and signalling of insulin.”
“ Magnesium depletion has a negative impact on glucose homeostasis and insulin sensitivity in diabetic patients.”
“ Magnesium improves glycemic control in diabetics and insulin sensitivity in insulin resistant subjects.”
“This study suggests that magnesium and calcium intake specifically, but not dairy intake, is associated with insulin sensitivity.”
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