Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Insulin and Lysine

drug:

Insulin

supplement:

Lysine

Research Papers that Mention the Interaction

Basic amino acids improved insulin solubility in water while 200 and 400 μg/mL lysine significantly increased insulin solubility in HBSS.
Scientific reports  •  2016  |  View Paper
Insulin increased NO synthesis and caused endothelium‐dependent vessel relaxation and reduced U46619‐induced contraction, effects blocked by NEM and L‐lysine , and dependent on extracellular L‐arginine.
Journal of cellular physiology  •  2011  |  View Paper
Insulin treatment increases α-tubulin Lysine 40 acetylation, a mechanism that was observed to be regulated by a counterbalance between GSK3 and mTOR, and led to microtubule stabilization.
Molecular & Cellular Proteomics  •  2019  |  View Paper
In the presence of insulin , cellular ATP levels were significantly increased by L-Arg, L-Glu, and L-Lys as well.
The American journal of physiology  •  1995  |  View Paper
Bovine insulin (100 mu u ml‐1) increased the maximal transport rate (Vmax = 3.49 +/‐ 0.30 mumol min‐1 g‐1, n = 4, P < 0.05) for L‐lysine 1.6‐fold without altering the Km.
Experimental physiology  •  1995  |  View Paper
D,L-arginine and L-lysine , introduced into the alimentary canal (IAC), caused significant secretion of insulin in rabbits, whereas D,L-methionine or L-phenylalanine evoked only a small effect.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society  •  1993  |  View Paper
Insulin stimulates the incorporation of lysine from the 29th day and of glycine from the 31st day of gestation onwards.
Archives internationales de physiologie et de biochimie  •  1976  |  View Paper
We observed that while the salt bridges formed by the lysine as an additive contributed more toward the direct interactions with insulin , the cation-π was more prominent for the insulin-arginine interactions.
The Journal of chemical physics  •  2021  |  View Paper
Insulin treatment increases α-tubulin Lysine 40 acetylation, a mechanism that was observed to be regulated by a counterbalance between GSK3 and mTOR, and led to microtubule stabilization.
Molecular & cellular proteomics : MCP  •  2019  |  View Paper
The effect of lysine on hormone production and activities is reflected by the change of plasma concentrations of insulin and insulin-like growth factor 1.
SpringerPlus  •  2015  |  View Paper
Show More