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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Insulin
supplement:
L-Epicatechin
Research Papers that Mention the Interaction
“ EC improves tissue insulin sensitivity by inhibiting inflammation, ER and oxidative stress.”
(–)‐Epicatechin in the control of glucose homeostasis: Involvement of redox‐regulated mechanisms“The flavanol-3-ol (-)-epicatechin (EC) can improve insulin sensitivity both in humans and animal models of T2D.”
“These results demonstrate that MF, EGCG and ECG are potentially able to enhance targeting combination of insulin with L02 cells and improve insulin sensitivity in L02 cells.”
“In conclusion, our data suggest that (-)-catechin promotes adipocyte differentiation and increased sensitivity to insulin in part by direct activation of PPARgamma, which could be at the basis of the observed pharmacological benefits of green tea intake in reducing the risk of type 2 diabetes.”
“Evidence from studies in humans and experimental animals suggest that consumption of the flavan-3-ol (-)-epicatechin (EC) and of EC-rich foods may improve insulin sensitivity.”
(-)-Epicatechin improves insulin sensitivity in high fat diet-fed mice.“In contrast, treatment with insulin and SNP significantly increased EC protein S-nitrosylation, the colocalization of S-nitrosothiol (S-NO) and protein-tyrosine phosphatase 1B (PTP1B), and Akt phosphorylation at Ser473 and inhibited PTP1B activity.”
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