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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Insulin and Ascorbate

drug:

Insulin

supplement:

Ascorbate

Research Papers that Mention the Interaction

It is also important to highlight that in regard to glucose monitoring, FSBG readings will be erroneously elevated following IV ascorbate use and insulin should not be administered to patients based on these readings.
Journal of the American College of Nutrition  •  2013  |  View Paper
The cellular uptake of ascorbate is regulated by both glucose and insulin (see for reviews Cunningham, 1998; Wilson, 2005).
British journal of pharmacology  •  2006  |  View Paper
In contrast, a 4-hour preincubation with ASC (1 mM) augmented the signal from pS473-Akt and pS63, pS73-c-Jun, when both insulin and H2O2 were added.
Life sciences  •  2005  |  View Paper
Insulin increased the intracellular concentration of ascorbate derived from DHAA and also increased the initial rates of uptake of DHAA and 2-deoxyglucose, but not that of ascorbate.
Endocrinology  •  1998  |  View Paper
In the presence of ascorbate , the amount of insoluble collagen increases, while the insoluble elastin content is significantly less.
The influence of ascorbate on insoluble elastin and collagen has been described.
Biochimica et biophysica acta  •  1985  |  View Paper
However, at 2 micrograms ascorbate per ml, the integrity of the insoluble elastin is lost and lysyl oxidase activity is decreased.
In the presence of ascorbate , there is an increase in collagen synthesis with a concomitant decrease in insoluble elastin and lysyl oxidase activity in cultured rabbit aortic smooth muscle cells.
Biochimica et biophysica acta  •  1984  |  View Paper