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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Insulin and Amino Acid Derivative

Research Papers that Mention the Interaction

These studies have suggested a role of the extended conformation of the A chain of insulin in causing a mobility shift of the acidic derivatives in this series.
International journal of peptide and protein research  •  1996  |  View Paper
Perfusions carried out in the single-pass mode with graded levels … that the acceleration of RNA degradation over the full range of amino acid deprivation (0 to 10X normal levels) was the same as that for … 3.15% h-1, respectively), and both were equally suppressed by insulin (2.…).
The Journal of biological chemistry  •  1987  |  View Paper
In fact, S-(23-27), S-(24-27), and S-(25-27) inhibited the islet glutamate dehydrogenase activity, the activation by which amino acids and amino acid derivatives are known to elicit a potentiation of insulin release.
The American journal of physiology  •  1986  |  View Paper
Thus, amino acid deprivation appears specifically to enhance the ability of insulin to stimulate amino acid transport in cultured adipocytes.
Endocrinology  •  1983  |  View Paper