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“These studies have suggested a role of the extended conformation of the A chain of insulin in causing a mobility shift of the acidic derivatives in this series.”
International journal of peptide and protein research • 1996 | View Paper
“Perfusions carried out in the single-pass mode with graded levels … that the acceleration of RNA degradation over the full range of amino acid deprivation (0 to 10X normal levels) was the same as that for … 3.15% h-1, respectively), and both were equally suppressed by insulin (2.…).”
The Journal of biological chemistry • 1987 | View Paper
“In fact, S-(23-27), S-(24-27), and S-(25-27) inhibited the islet glutamate dehydrogenase activity, the activation by which amino acids and amino acid derivatives are known to elicit a potentiation of insulin release.”