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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Inosine
drug:
Norepinephrine
Research Papers that Mention the Interaction
“ Inosine increased rather than decreased the potency of norepinephrine while decreasing its maximal effect.”
Antagonism of the positive chronotropic effect of norepinephrine by purine nucleosides in rat atria.“3 Inclusion of inosine (10 mm) in the hypoxic perfusion medium increased significantly the rate and extent of post‐hypoxic recovery of the pressor response to NA.”
“Uridine and inosine in concentrations of 10(-4) M inhibited the epinephrine (10(-5) M)-, the norepinephrine (10(-5) M)- and the theophylline (10(-3) M)-stimulated lipolysis.”
“Moreover, norepinephrine requirement was lower in the iNO group than in the control group (p = 0.0060).”
Inhaled nitric oxide improves pulmonary hypertension and organ functions after adult heart valve surgeries“Cytidine, inosine , and uridine triphosphate facilitated uptake of NA to a similar degree as adenosine diphosphate but less than adenosine triphosphate.”
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