Discover Supplement-Drug Interactions
The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided…
2 months ago
Possible Interaction: Inosine and Methotrexate
Research Papers that Mention the Interaction
“The protecting agents employed, thymidine and
, circumvent the antipurine and antipyrimidine effects of
, but neither agent inhibits the transport or the polyglutamylation of MTX.”
Analysis of "early" thymidine/inosine protection as an adjunct to methotrexate therapy.
Cancer treatment reports • 1985 |
“It is concluded that co-administration of
and/or thymidine allows the use of
otherwise not tolerated, though with loss of anti-tumor effect.”
Influence of concomitant infusion of thymidine and inosine on methotrexate activity in normal and P388-bearing mice.
European journal of cancer & clinical oncology • 1984 |
“The infusion of
alone or in combination with thymidine blocked both the toxicity and antitumor activity of
Potentiation of the antitumor activity of methotrexate by concurrent infusion of thymidine.
Cancer research • 1978 |
Help us improve
, we'd love to hear your feedback: