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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Inosine
drug:
Isoproterenol
Research Papers that Mention the Interaction
“In addition, isoproterenol caused a 2-3-fold increase in inosine and hypoxanthine production which was concentration-dependent and could be inhibited by propranolol.”
Purine accumulation in human fat cell suspensions. Evidence that human adipocytes release inosine and hypoxanthine rather than adenosine.“ Isoproterenol further increased the adenosine and inosine release from both age groups.”
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.“ Isoproterenol has a more marked effect on the metabolism of adenine nucleotides in the heart only: it reduced the amount of adenine nucleotides and enhanced their synthesis from inosine.”
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