“The antitumor activity of 5′-DFUR was markedly enhanced by coadministration of inosine or guanosine.”
“The increase in lifespan (…) of mice treated with 5′-DFUR was augmented by the … with guanosine or inosine in a dose-dependent fashion, and the maximum ILS was about 160% with the combination, while … in the case of 5′-DFUR alone was only 48% in the P388 leukemia system.”