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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Indomethacin
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“However, insignificant spectral changes of the reference compounds (ADC-6 and ADC-2) initiated by HSA implied that indomethacin played critical role in the identification of HSA.”
“The competitive assays and molecular docking results reveal that the indomethacin in ADC-IMC-6 could tightly combine at drug site I of HSA.”
Selective bioimaging of cancer cells and detection of HSA with indomethacin-based fluorescent probes.“For example, indometacin renders cinnamic acid to make reposition, and decreases binding affinity of HSA for cinnamic acid, but increases binding affinity of itself to HSA.”
“The results of fluorescence titration revealed that indomethacin , strongly quench the intrinsic fluorescence of HSA by static quenching and nonradiative energy transfer.”
“A small decrease in the binding of drug to the guanidinated preparation also confirms the involvement of positive charge, probably contributed by lysine residue(s), in the binding of indomethacin to HSA.”
“5 The release of TxA2 from PAM was increased by anti‐DNP IgE and DNP‐HSA , an effect that was prevented by indomethacin.”
IgE‐dependent activation of alveolar macrophages augments neurally mediated contraction of small airways“Pretreatment with indomethacin significantly enhanced the affinity of antibodies produced 21 days after immunization with human serum albumin ( HSA).”
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