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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Indomethacin
supplement:
Methionine
Research Papers that Mention the Interaction
“The noradrenaline output was enhanced after perfusion of the hearts with indometacin 3× 10−5 M indicating blockade of the prostaglandin-mediated negative feedback control.”
“The M phi-induced vasodilation of the lymph nodes was significantly reduced by 12 h preincubation of the macrophages with 5 x 10(-5) M N omega-nitro-L-arginine methyl ester (L-NAME), 10(-5) M indomethacin , 10(-6) M dexamethasone, or 10(-5) M cycloheximide.”
“The effect was blocked by a 30-min incubation of explants with 10−6 M indomethacin.”
“When endogenous prostaglandin synthesis was inhibited by 10−6 M indomethacin , the anti‐TNP IgE response, but not the corresponding IgG response, was suppressed by 30%‐60%.”
“The level of prostaglandins produced in vitro, as measured by RIA, was 10− M and was found to be completely blocked by indomethacin.”
Prostaglandin-mediated regulation of the mixed lymphocyte culture and generation of cytotoxic cells.“ Indomethacin at concentrations of about 10 −4 M lowered ADP:O ratio and stimulated state 4 oxidation.”
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