supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Indomethacin
supplement:
Docosahexaenoic Acid
Research Papers that Mention the Interaction
“ Indomethacin , a cyclooxygenase inhibitor, is ineffective in blocking the apoptosis induced by DHA , suggesting that DHA-induced apoptosis in HT-29 cells is not mediated through the cyclooxygenase pathway.”
Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells.“An isobolographic analysis was performed to characterize the antinociceptive interaction between DHA and indomethacin.”
Synergistic antinociceptive effect and gastric safety of the combination of docosahexaenoic acid and indomethacin in rats“Inhibition of nitric oxide synthesis by N•-nitro-L-arginine methyl ester hydrochloride (100 mol/l) had no effect on DHA relaxations; however, indomethacin or nifedipine caused significant inhibition at• 30 mol/l DHA.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback