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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Indomethacin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Despite a low calcium diet, daily urinary calcium excretion was enhanced during and after withdrawal of indomethacin treatment (median 6.3, range 5.3 to 14, and median 9.4, range 4.4 to 38 mg/kg per day, respectively).”
Calcium homeostasis and hypercalciuria in hyperprostaglandin E syndrome.“3 The ATP‐dependent uptake of Ca by membranes derived from guinea‐pig aortic or gastric smooth muscle or from human umbilical arterial muscle was inhibited by indomethacin in a concentration‐dependent manner.”
“The endothelial membranes took up added Ca in the presence of added ATP and this uptake was inhibited by indomethacin and also by members of a group of pharmacologically‐related drugs.”
“Since both hydrochlorothiazide [2, 3] and indomethacin [4, 5] interfere with calcium , the role of calcium in the aetiology of intracranial calcification should be explored in future studies as well as the effect of the hypernatraemia,”
“Since both hydrochlorothiazide [2, 3] and indomethacin [4, 5] interfere with calcium , the role of calcium in the aetiology of intracranial calcification should be explored in future studies as well as the effect of the hypernatraemia,”
“Under indomethacin intervention, the levels of intracellular free calcium showed a significant increase.”
“ Indomethacin decreases significantly the urinary calcium excretion in hypercalciuric patients.”
“In calcium ion-induced contractions, indometacin pretreatment increased CuZnSOD, GSH-Px and GR activities.”
Effect of indometacin pretreatment on protamine sulfate-mediated relaxation of the isolated rat uterus: the role of the antioxidative defense system.“The deposit of calcium in experimental granulomas as determined by X-ray fluorescence is notably decreased by orally given indomethacin and diflunisal.”
“ Calcium and magnesium outputs, although did not differ from the controls, nevertheless decreased significantly with indomethacin (P<0.01).”
“It was found that indomethacin reduced the release of calcium , inorganic phosphate and hydroxyproline without affecting the total amount of hydroxyproline in the cultures.”
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