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“ Indomethacin reduced the potentiating effect of AA only at P2-4, while caffeic acid and baicalein showed no apparent effect, indicating that metabolites of the cyclooxygenase pathway contribute to INMDA potentiation at P2-4.”
“The negative inotropic effect of AA was enhanced 500-fold by the coadministration of indomethacin (cyclo-oxygenase inhibitor) and caffeic acid (lipoxygenase inhibitor).”